Antigenemia in paracoccidioidomycosis

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Antigenemia in paracoccidioidomycosis.

Severe forms of paracoccidioidomycosis (Pcm) are accompanied by intense immunological involvement characterized by depression of the cell-mediated immune response and by high levels of antibodies in serum with no protective function. These changes can be reversed by antifungal treatment. It has been suggested that antigens of Paracoccidioides brasiliensis released into the circulation during th...

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Monitoring gp43 antigenemia in Paracoccidioidomycosis patients during therapy.

Paracoccidioidomycosis (PCM) is a systemic fungal disease that is particularly important among individuals living and working in rural areas of endemicity in Latin America. Detection of anti-Paracoccidioides brasiliensis antibodies is of limited value due to false-negative results. Detection of P. brasiliensis-gp43 circulating antigen is a practical approach for a specific diagnosis of the dise...

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ژورنال

عنوان ژورنال: Journal of Clinical Microbiology

سال: 1992

ISSN: 0095-1137,1098-660X

DOI: 10.1128/jcm.30.2.381-385.1992